Cleaning Device

A variety of standard configurations are available to meet requirements for WIP (Wash-in-Place), SIP (Steam/Sterilize-in-Place), CIP (Clean-in-Place), or Sterilize-in-Place, while meeting different process requirements such as mounting orientation and process drain and ventilation needs.

Reduced Risk of Cross-Contamination and Operator Exposure

Allows the active valve halves to be opened and closed in a sealed environment for fully contained cleaning of hazardous product residues. Cleaning can be done in-place prior to safe removal of the active valve halves to protect the operator, or between batch activities as part of a qualified process (determined by the customer), either way helping to reduce the risk of cross-contamination within the facility.

Maximized Cleaning Effectiveness

The simple GMP design maximizes the surface area of ​​the active unit exposed to the cleaning cycle, enhancing cleaning effectiveness in product contact and sealing areas. This is achieved through a unique sealing approach around the periphery of the device, eliminating the need for typical seat/disc assemblies that would otherwise prevent successful cleaning in a fully passive unit design.
Improved Sterility Assurance

As a critical step in the aseptic manufacturing process, the Active Clean Cap Accessory has the unique capability to open the active tray for effective sterilization, allowing the active valve to be steam sterilized in place or decontaminated with the process stream (e.g. using an isolator) while maintaining sterile boundaries when the valve is closed and the accessory removed prior to the powder transfer process.